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Side effects of Augmentin
Augmentin may cause additional side effects, including:
Also, Augmentin may lead to an overgrowth of bacteria called Clostridium difficile. This can cause severe diarrhea that requires treatment to prevent complications.
It is essential to report any severe side effect to a doctor.
The United States Food and Drug Administration note that, while Augmentin has a low risk of toxicity, people who take it for a longer period should be under close supervision, as there may be a chance of damage to the kidney or liver.
Administration
Bactericidal antimicrobials, such as amoxicillin, often are most effective in a “time-dependent” manner rather than a “concentration-dependent” manner. augmentin over the counter Time-dependent refers to the time that serum concentrations exceed the minimum-inhibitor-concentration (MIC) for the microorganism. Therefore, they are often dosed more frequently, rather than the concentration-dependent drugs, which can be dosed, for example, daily. The more “around-the-clock” dosing provides minor variation in peak and trough serum concentrations.
Amoxicillin is an oral antimicrobial; whereas, ampicillin (which is structurally similar) can be given orally, intravenously, or intramuscularly. Amoxicillin comes in immediate-release or extended-release tablets. It also comes in a chewable tablet or a suspension. It may be mixed (after thoroughly shaking) and administered with formula, milk, water, fruit juice, ginger ale, or other cold drinks if given in suspension. The administration should take place immediately after mixing. Patients should not crush Extended-release tablets, and the administration should be within 1 hour after finishing a meal. Amoxicillin is sometimes preferred over penicillin in children because of its taste.
Dosing in Renal Impairment
Geriatric Consideration
Breastfeeding
Bone and joint infections
Augmentin 625 is used to treat infections in the Bone and joint infections caused by Streptococci and Staphylococci strains of bacteria
Phenylketonurics
Skin And Skin Structure Infections
Caused by beta lactamase–producing isolates of Staphylococcus aureus, Escherichia coli, and Klebsiella species.